Sridhar Mani Selected Research

CEP 2563

11/2004

Phase I clinical trial of CEP-2563 dihydrochloride, a receptor tyrosine kinase inhibitor, in patients with refractory solid tumors.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Sridhar Mani Research Topics

Disease

62	Neoplasms (Cancer) 10/2021 - 04/2002
27	Inflammation (Inflammations) 02/2022 - 07/2011
14	Colitis 12/2022 - 06/2013
10	Diarrhea 12/2020 - 04/2003
8	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2022 - 06/2013
8	Colorectal Neoplasms (Colorectal Cancer) 12/2020 - 02/2003
7	Breast Neoplasms (Breast Cancer) 01/2017 - 07/2002
6	Adenocarcinoma 05/2020 - 04/2003
6	Colonic Neoplasms (Colon Cancer) 10/2019 - 10/2002
4	Carcinoma (Carcinomatosis) 04/2020 - 04/2003
4	Infections 01/2020 - 01/2014
4	Neutropenia 06/2013 - 04/2002
4	Fatigue 10/2010 - 09/2003
3	Ulcerative Colitis 01/2020 - 09/2014
3	Body Weight (Weight, Body) 01/2020 - 11/2014
3	Neoplasm Metastasis (Metastasis) 06/2016 - 08/2003
3	Pancreatic Neoplasms (Pancreatic Cancer) 04/2010 - 02/2003
2	Necrotizing Enterocolitis 01/2022 - 01/2018
2	Dysbiosis 10/2021 - 01/2019
2	Liver Neoplasms (Liver Cancer) 10/2021 - 10/2005
2	Crohn Disease (Crohn's Disease) 11/2017 - 09/2014
2	Bacterial Infections (Bacterial Infection) 01/2017 - 01/2016
2	Drug-Related Side Effects and Adverse Reactions 01/2016 - 11/2010
2	Cholangiocarcinoma 12/2012 - 12/2004
2	Liver Diseases (Liver Disease) 05/2012 - 08/2003
2	Disease Progression 02/2012 - 04/2010
2	Rhabdoid Tumor (Rhabdoid Tumors) 11/2010 - 01/2008
2	Fever (Fevers) 10/2010 - 01/2003
2	Hypoxia (Hypoxemia) 08/2009 - 11/2008
2	Ovarian Neoplasms (Ovarian Cancer) 09/2008 - 02/2004
2	Stomatitis 02/2007 - 01/2003
2	Hepatocellular Carcinoma (Hepatoma) 02/2007 - 09/2005

Drug/Important Bio-Agent (IBA)

19	Pregnane X ReceptorIBA 02/2022 - 09/2005
19	Pharmaceutical PreparationsIBA 02/2022 - 07/2002
10	XenobioticsIBA 02/2022 - 09/2005
8	Dextran SulfateIBA 01/2020 - 01/2014
8	Irinotecan (Camptosar)FDA LinkGeneric 06/2013 - 10/2002
6	CytokinesIBA 01/2021 - 02/2015
6	Toll-Like Receptor 4IBA 01/2020 - 08/2013
6	EnzymesIBA 12/2019 - 04/2003
6	LigandsIBA 01/2019 - 05/2003
6	Peroxidase (Myeloperoxidase)IBA 11/2017 - 01/2014
5	Messenger RNA (mRNA)IBA 12/2020 - 08/2013
5	Proteins (Proteins, Gene)FDA Link 12/2020 - 07/2002
5	Cytochrome P-450 CYP3AIBA 11/2020 - 09/2005
5	ixabepilone (BMS 247550)FDA Link 01/2009 - 07/2002
5	Oxaliplatin (Eloxatin)FDA LinkGeneric 08/2007 - 07/2003
4	FlavonoidsIBA 01/2020 - 01/2012
4	Dextrans (Dextran)FDA Link 01/2017 - 01/2012
4	Interleukin-6 (Interleukin 6)IBA 10/2015 - 06/2013
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2015 - 02/2004
4	Paclitaxel (Taxol)FDA LinkGeneric 04/2010 - 02/2004
4	Docetaxel (Taxotere)FDA Link 03/2006 - 01/2003
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 02/2022 - 08/2011
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 01/2014
3	Biological ProductsIBA 01/2020 - 02/2004
3	Sulfonic AcidsIBA 11/2017 - 06/2013
3	alvocidib (flavopiridol)IBA 11/2010 - 07/2002
3	taxaneIBA 10/2010 - 02/2004
3	Capecitabine (Xeloda)FDA Link 06/2007 - 10/2002
3	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 09/2006 - 09/2003
2	Bile Acids and Salts (Bile Acids)IBA 02/2022 - 01/2018
2	IndolesIBA 01/2021 - 05/2020
2	Tryptophan (L-Tryptophan)FDA Link 01/2021 - 01/2019
2	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 04/2020 - 10/2019
2	Pregnenolone Carbonitrile (PCN)IBA 01/2020 - 10/2016
2	Hormones (Hormone)IBA 12/2019 - 01/2017
2	baicaleinIBA 11/2017 - 01/2012
2	ErbB Receptors (EGF Receptor)IBA 01/2017 - 06/2003
2	SodiumIBA 01/2017 - 08/2013
2	Phosphotransferases (Kinase)IBA 02/2015 - 07/2002
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 08/2013 - 06/2013
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 08/2013 - 06/2013
2	Nitric Oxide Synthase (NO Synthase)IBA 08/2013 - 06/2013
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 06/2013 - 01/2012
2	Bortezomib (Velcade)FDA Link 05/2012 - 12/2011
2	Protein Kinases (Protein Kinase)IBA 10/2010 - 08/2004
2	CreatinineIBA 02/2008 - 08/2003
2	Imatinib Mesylate (Gleevec)FDA Link 02/2008 - 01/2002
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2008 - 07/2002
2	CyclinsIBA 01/2008 - 07/2002
2	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2007 - 09/2006
2	9-aminocamptothecinIBA 05/2006 - 08/2004
2	Antineoplastic Agents (Antineoplastics)IBA 04/2006 - 11/2004
2	GEM231IBA 03/2006 - 09/2003
2	Antisense OligonucleotidesIBA 03/2006 - 04/2002
2	epothilone B (EPO906)IBA 09/2005 - 02/2004
2	Gemcitabine FDA Link 12/2004 - 02/2003
2	TubulinIBA 07/2004 - 07/2002
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 12/2022
1	choloylglycine hydrolaseIBA 02/2022
1	Constitutive Androstane ReceptorIBA 02/2022
1	Taurine FDA Link 02/2022
1	tilimycinIBA 01/2022
1	Enterotoxins (Enterotoxin)IBA 01/2022
1	Cytotoxins (Cytolysins)IBA 01/2022
1	tilivallineIBA 01/2022

Therapy/Procedure

16	Therapeutics 01/2017 - 04/2002
12	Drug Therapy (Chemotherapy) 01/2019 - 01/2003
3	Radiotherapy 09/2006 - 06/2003